产品货号：
Z39518
中文名称：
PTPN6抗体
英文名称：
Anti-PTPN6 Antibody (Clone#8H11B10)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PTPN6 Antibody (Clone#8H11B10) |
| 指标别名 | HCP;HCPH;HPTP1C;PTP 1C;PTP1C;PTPN6;SH PTP1;SHP 1;SHP 1L;SHP1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | PTPN6 |
| 克隆号 | 8H11B10 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human SHP1/PTPN6 recombinant protein (Position:E67-K572). |
| 实际分子量 | 68KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Tyrosine-protein phosphatase non-receptor type 6,also known as Src homology region 2 domain-containing phosphatase-1 (SHP-1),is an enzyme that in humans is encoded by the PTPN6 gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth,differentiation,mitotic cycle,and oncogenic transformation.N-terminal part of this PTP contains two tandem Src homolog (SH2) domains,which act as protein phospho-tyrosine binding domains,and mediate the interaction of this PTP with its substrates.This PTP is expressed primarily in hematopoietic cells,and functions as an important regulator of multiple signaling pathways in hematopoietic cells.This PTP has been shown to interact with,and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling.Multiple alternatively spliced variants of this gene,which encode distinct isoforms,have been reported. |
| Uniprot ID | P29350 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | protein tyrosine phosphatase non-receptor type 6 |
| 蛋白名全称 | Tyrosine-protein phosphatase non-receptor type 6 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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